SweetTrip is reader-supported and I sometimes use affiliate links. When you buy a product through these links, I may earn a small commission at no additional cost to you. I only recommend products I would use myself and all opinions expressed are my own.

The Best CBD Creams for Neuropathy Pain & Nerve Repair

Best CBD creams for neuropathy foot pain

Good news: CBD works great on neuropathy pain! Whether you prefer ingesting drops of pure CBD oil or rubbing your feet with CBD cream for pain, a wide choice of CBD products is now available to help relieve neuropathy pain and damaged nerves. 

As usual, I’ve investigated and scrutinized dozens of CBD pain relief creams to find the ones that best target neuropathy pain and discomforts. Without further ado, here are 10 CBD pain-relieving topicals to choose from if you suffer from nerve pain!

#1. Best CBD Cream for Neuropathy Pain & Nerve Repair

Zatural Broad Spectrum CBD Hot Cream - 2000 mg

CBD Cost & Concentration

Zatural CBD Hot Cream - 2000 mg

Zatural CBD Hot Cream is the most potent and effective CBD cream for neuropathy problems. First, it’s made with high-quality CBD that’s organically grown in Colorado (USA) and Supercritical CO2 extracted. It’s the purest way to extract CBD oil and preserve its natural properties. This cream is infused with broad-spectrum CBD. It does not contain any THC but does contain some terpenes and flavonoids which work in synergy with the CBD to enhance relief and reduce inflammation. 

Besides the CBD itself, Zatural’s Hot Cream features over 20 plant extracts and essential oils from which we find highly valuable benefits for neuropathy-related problems. I’m referring to Helichrysum flower oil, believed to help regenerate nerves and connective tissues, as well as Basil, known as a good nerve tonic. There’s also Peppermint oil to help boost blood circulation, and Chamomille for its incredible soothing properties. Add to that some Menthol crystals and Aloe Vera extract and you’ve got the perfect neuropathy combo!

If you choose the maximum strength (2000 mg / 8 oz), Zatural cream is quite expensive ($90). But if you calculate the actual cost per 100 mg of CBD, it’s the best price you can get by far ($4,5). You’re actually buying CBD, not water!

Zatural Quick Relief CBD Roll-on - 200 mg

Zatural also offers a very good Quick Relief CBD Roll-on that’s ideal to carry in your bag or pocket and to use on the go. You get the same quality and a similar synergy for neuropathy between CBD and essential oils. However, the actual CBD concentration is lower (154 mg of CBD per ounce versus 250 mg for the Hot Cream), and the cost per 100 mg of CBD is double ($9.99 versus $4.5). 

CBD Cost & Concentration

2. Best Low-strength CBD Isolate Foot Cream for Nerve Pain

Pure Hemp Isolate CBD Intensive Relief Rub with Emu Oil - 500 mg

CBD Cost & Concentration

Pure Hemp CBD Intensive Relief Cream - 500 mg

Pure Hemp is an award-winning CBD company that offers an extended catalog of first-quality CBD products. There are over 10 CBD pain relief topicals to choose from on their website.

I find the 500 mg Intensive Relief Cream to be the most suitable if you’re beginning with CBD. It’s made with CBD isolate, the purest form of CBD guaranteed without any traces of THC residues. It also contains 10% of Emu oil, which has strong anti-inflammatory properties, and helps stimulates cells regeneration. This CBD cream features aloe vera and arnica for even stronger pain relief effects, as well as menthol for a discrete cooling sensation. 

The strength is medium. If you’re looking for a similar product with a higher CBD potency, check out Pure Hemp’s Full Spectrum CBD Freeze Relief Cream with 1000 mg

3. Best Medium-strength CBD Topical Cream for Neuropathy Pain

Soul CBD Rapid Relief CBD Cream - 1500 mg

CBD Cost & Concentration

Soul CBD Rapid Relief CBD Cream - 1500 mg

Mike, the founder of Soul CBD is a professional boxer who got diagnosed with ankylosing spondylitis, an autoimmune disease where the spine and other areas of the body become inflamed. He found incredible physical relief and mental benefits in CBD, and later founded Soul CBD with his sister Angie to “share his knowledge while helping others to defeat whatever battle with pain they may be facing“. Talking about battle with pain, we, diabetes and neuropathy patients, know quite a lot!

Soul CBD Rapid Relief 1500 mg CBD cream is a success! The formula is simple, organic, and clean. It’s made with 1500 mg of pure CBD isolate (no THC, no terpenes, no nothing!) infused in 3.4 fluid ounces of cream. That makes an actual CBD concentration of 441 mg per ounce, which is medium strength. 

This relief cream also contains Menthol, Eucalyptus essential oil, as well as Arnica, a great analgesic combo. As often in CBD pain topicals, we find soothing Aloe Vera. There’s a bonus ingredient here: Shea Butter, which is an amazing skin moisturizer.

Soul CBD 1500 mg Cream is a great product if you’re looking for a medium-strength CBD cream for neuropathy that combines pain-relieving, soothing, and moisturising effects!

4. Strongest & Most Potent CBD Cream for Neuropathy

CbdMD Topical Relief Roll-on with Lidocaine - 3000 mg

CBD Cost & Concentration

CbdMD Topical Relief Roll-on with Lidocaine - 3000 mg​

CbdMD is another leading CBD company with a wide catalog of CBD topicals and pain relievers. With an actual CBD concentration of 1200 mg per ounce, CbdMD Topical Relief Roll-on is pone of the strongest CBD topicals for pain on the market. 

It’s made with superior broad-spectrum CBD extracted from USA-grown cannabis plants. The additional 4% of Lidocaine, a local anesthetic, makes it a very potent and immediate pain reliever. It also features Aloe Vera and Chamomille flower extracts to soothe and calm nerve pain, as well as cucumber fruit extract for its cooling effect on the skin. It’s a great combination to locally target neuropathic pain in the feet or hands. 

It’s a powerful product for those who are already familiar with CBD or suffer from strong diabetic or neuropathy foot pain. You can apply up to 4 times a day. Last but not least, the cost per 100 mg of CBD is unbeatable ($4,33!). 

5. Best Full Spectrum CBD & THC Cannabis Salve for Nerve Pain

NuLeaf Naturals Full Spectrum CBD Salve for Pain - 900 mg

CBD Cost & Concentration

NuLeaf Naturals Full Spectrum CBD Salve for Pain - 900 mg​

If you like minimalist cosmetics with efficient formulas, NuLeaf Naturals’ full-spectrum CBD balm is your new favorite!

We could not do simpler: 900 mg of Full-spectrum Organic CBD infused in pure Shea Butter. Nothing more. No perfume, no preservatives, no chemicals, no nothing irritative. And guess what? It works just great! 

Full-spectrum CBD contains small amounts of all components naturally found in the cannabis plant, including traces of THC (tetrahydrocannabinol). Legal full-spectrum CBD products cannot have more than 0.3% of THC. Such a small quantity won’t provoke any “high” effect. Instead, it works in synergy with CBD and other components to increase the pain-relieving powers of the cannabis plant. The CBD used in NuLeaf Balm is organic, premium quality, and supercritical Co2 extracted. 

This balm is highly concentrated and its travel size jar is ideal to carry everywhere with you. Apply a small quantity and gently massage your feet. One jar goes a long way!

6. Best Cryotherapy Freeze CBD Cream for Immediate Nerve Pain Relief

Pure Hemp Full Spectrum CBD Freeze Relief Cream - 1000 mg

CBD Cost & Concentration

Pure Hemp Full Spectrum CBD Freeze Relief Cream - 1000 mg

Cold therapy, or cryotherapy, has proven great pain-relieving effects on neuropathy foot pain. Many people with neuropathy suffer from stabbing or shooting pain, and burning sensation in the feet. Cold has strong immediate analgesic effects that temporarily alleviate and neutralize nerve pain symptoms. 

Pure Hemp has managed to combine CBD and cryotherapy together for an ultimate pain relief cream. It uses full-spectrum high-quality CBD (actual concentration of 588 mg per ounce), as well as Menthol crystals, Arnica & Peppermint oil for a freeze cooling feeling. 

Add to that moisturizing shea butter, avocado oil, and soothing aloe vera and you’ve got an amazing all-in-one neuropathy foot cream

Pure Hemp is a premium-quality CBD company, so this cream is quite expensive ($100 for 1.7 oz) but you currently get 50% off Pure Hemp website, so take advantage of it now!

7. Most affordable CBD Pain Relief Roll-on for Diabetic Feet & Neuropathy

Savage CBD Full Spectrum CBD Roll-on - 750 mg

CBD Cost & Concentration

Savage CBD Full-spectrum CBD Roll-on - 750 mg

Savage CBD is another trustable CBD company that’s been here since the beginning of the CBD era and featured by Forbes. It stands out for its considerably lower prices than the competition, but does not compromise on quality. 

This CBD pain relief roll-on is the most affordable CBD topical for nerve pain. It’s infused with 750 mg of full-spectrum CBD for an actual CBD concentration of 250 mg per ounce which is medium strength. It also features cooling essential oils as well as soothing aloe vera

The portable roll-on format makes it easy to carry everywhere and to apply on the go whenever needed. Bonus: it smells very nice! 

Savage CBD also offers a Full-spectrum CBD balm, as well as a Lavender Full-spectrum CBD lotion at low costs. However, their actual CBD concentration might be too low to be effective on nerve pain (75 mg per ounce for the balm, and 37,5 mg per ounce for the lotion). 

8. Best Therapeutic CBD Hemp Oil for Neuropathy in Feet

CBDMedic Pain Relief CBD Oil with Frankincense & Myrrh - 200 mg

CBD Cost & Concentration

CBDMedic Pain Relief CBD Massage Oil with Frankincense & Myrrh - 200 mg

Looking at the list of ingredients, it looks like CBDMedics has formulated this therapeutic pain relief CBD massage oil specially for neuropathy patients!

It does not have a high CBD concentration (only 57 mg per ounce), but the synergy with 3% of Camphor and 4% of Menthol, two strong external analgesics works wonders to neutralize nerve pain. Plus, it’s the only CBD topical I’ve found that contains Frankincense and Myrrh essential oils, the 2 most used essential oils in aromatherapy treatments for neuropathy

Frankincense has strong sedative properties and contains great quantities of terpenes and boswellic acid which are potent anti-inflammatory. It’s also believed to improve message transmission from the nerves to the brain and thus help reduce nerve pain. 

Myrrh has been used in Ayurvedic and Chinese traditional medicines for centuries. Its natural compounds interact with our opioid receptors and help decrease the brain’s perception of pain. It also helps reduce swelling and provides a cooling effect on the skin that alleviates neuropathy discomforts such as tingling. 

Plus, CBDMedic uses premium luxurious carrier oils: jojoba, argan, cottonseed, and coconut. Without any doubt, the best CBD massage oil for people suffering from nerve pain in the feet and hands, at a very reasonable price!


9. Best CBD Foot Care Bundle for Neuropathy, Pinched Nerves & Nerve Pain

CBD.Co Topical CBD Bundle with 6 Foot Care Products

CBD Cost & Concentration

CBD.Co CBD Foot Care Bundle: Is it worth it?

The CBD Foot Care Bundle by CBD.co is a great starter kit for beginners willing to try CBD products. You get to try 6 different CBD foot care and pain relief products. They’re all of excellent quality from 4 leading CBD companies (Social CBD, Soul Spring CBD, CBD Medic, and CBD FX). 
The 2 foot & ankle pain relief topicals for CBD Medic are very good at targeting neuropathy foot problems. The Social CBD foot renewal cream and CBD FX overnight moisturizer foot balm are ideal foot creams for diabetic and neuropathic feet. And the soothing CBD foot bath soak and bath bomb are great for relaxing your feet and treating them with a luxurious moment. 
All in all, this bundle offer is a good choice and makes you save $29. However, it’s made for CBD newbies, so the products have low to medium CBD concentrations. If you want higher potencies, you should buy them separately and select a higher CBD dosage. 

10. Second Best CBD Foot Care Set for Diabetic Neuropathy & Nerve Pain

CBD FX Foot Care Set with CBD Foot Cream and CBD Foot Masks

CBD Cost & Concentration

CBD FX Foot Care Set with CBD Foot Cream and CBD Foot Masks​

CBD FX is a CBD company I often recommend to my readers for the wide variety of products made to suit everyone’s needs. The products are organic, cruelty-free, and made in the USA. 

CBD FX foot care set includes one CBD foot cream and two CBD foot masks. The foot cream by itself is well worth the price. It contains 500 mg of high-quality broad-spectrum CBD for an actual concentration of 294 mg per ounce (medium strength). Besides the pain-relieving properties of CBD, you’ll benefit from the soothing and anti-inflammatory effects of Lavender and Tea Tree essential oils, as well as the nourishing properties of shea butter and jojoba oil. 

CBD FX’s foot masks are easy-to-use moisturizing slip-on booties infused with 50 mg of broad-spectrum CBD each and essential oils. They’re made to smooth, calm, and soften your skin while relieving stress and sores. A luxurious treat for your feet!

How to Choose CBD Topicals for Neuropathy & Nerve Pain

You’ve probably noticed already: no CBD pain-relief cream has been specially formulated for neuropathic pain. When you know that more than 20 million Americans have some form of peripheral neuropathy, you can really wonder what the h*** CBD companies are waiting for. 

Fortunately, most CBD creams for pain do work on neuropathy symptom. Before buying CBD topicals for nerve pain, you should pay special attention to the potency, the type and the quality of CBD.

But, and maybe it’s the most important point, you should look for neuropathy-specific ingredients that work in synergy with CBD.

CBD potency: 50 mg, 1000 mg, or 3000 mg?

Most CBD topical pain relief products contain anything from 50 mg to 3000 mg of CBD. Careful! These numbers represent the quantity of CBD contained in the bottle. They’re not about potency! To know the real potency of the product, you must calculate the actual CBD concentration (how many mg of CBD per ounce).

Calculate a cream's actual CBD concentration

What has a real impact on pain is the product’s actual CBD concentration. In other words, the mg of CBD per ounce, and not the quantity of CBD per bottle. A travel-size 1-ounce pain-relieving balm infused with 500 mg of CBD is much stronger than an 8-ounces lotion infused with 1000 mg of CBD. In the first case, the actual CBD concentration is 500 mg per ounce (medium/strong), while in the second case it’s only 125 (low-strength). 

When shopping for CBD cream for pain, you should always do the maths and calculate the actual CBD concentration to know what’s the real potency. As you can see in the above list of CBD creams for neuropathy, I’ve calculated the mg of CBD per ounce of each product. Simply divide the number of mg of CBD by the number of ounces. To give you a general idea about the potency:

If you’re new to CBD, it’s recommended you start with lower CBD concentrations and gradually increase potency. 

CBD isolate versus full-spectrum versus broad-spectrum for neuropathy
The pain-relieving effects of CBD also depend on the type of CBD

CBD isolate, Broad-spectrum or Full-spectrum?

The type of CBD your cream is infused with is very important too. There are 3 main types of CBD: isolate, broad-spectrum, and full-spectrum. The difference relates to their compounds. 

CBD isolate, the purest form of CBD

CBD isolate is the purest form of CBD. This type of CBD contains Cannabidiols only. It’s much more refined than the other forms, and it comes through extra processing to isolate the Cannabidiol from any other cannabis plant natural compounds. 

Choose CBD isolate topicals for pain relief if: 

Full-spectrum CBD, the entourage effect

Full-spectrum CBD contains not only Cannabidiol, but also small amounts of all the naturals compounds found in the Cannabis plant, including Terpenes, Flavonoids, and traces of Tetrahydrocannabinol (THC). Studies have shown that full-spectrum CBD offers what’s known as the “entourage effects”. The synergy between all the cannabis plant’s compounds maximizes the benefits of CBD, especially for pain management.

A potential risk of full-spectrum CBD is the “high” effect due to THC. However, the quantity of THC is so little (less than 0,3%) that you would need to ingest or apply huge doses of creams to produce any euphoric effects. It’s pretty much impossible it happens using pain-relieving topicals. 

Choose Full spectrum CBD creams for pain relief if: 

Broad-spectrum CBD, a THC-free intermediate

Broad-spectrum CBD is like full-spectrum CBD but without the THC. It is not a pure CBD isolate as it does contain other cannabis compounds (including terpenes and flavonoids), but it has been cleared from any traces of THC. Using pain relief topicals infused with broad-spectrum CBD allows you to benefit from some of the entourage effects but not as much as with full-spectrum CBD. In other words, studies have shown that broad-spectrum CBD is a stronger pain reliever than CBD isolate, but not as strong as full-spectrum CBD. 

Choose Broad-spectrum CBD pain relievers if: 

Full Spectrum vs Broad Spectrum Vs CBD Isolate
Full-Spectrum CBD vs CBD Isolate

COA testings and CBD quality

CBD is a new world and new companies pop up every month. That context makes it hard to choose, trust, and be sure we’re buying quality products. That’s why third-party COAs (Certificates of Analysis) are very helpful. These reports help guarantee the cream you’re looking at contains what it says it contains. They also report whether the product passed tests for contaminants. All the CBD creams for the pain I’ve selected here have passed COAs that you can read on the companies’ website. 

Synergy ingredients to look for in CBD creams for Neuropathy

CBD isn’t the only natural pain reliever that works for neuropathy. So, why not look for a cream that combines CBD with other components that also relieve nerve pain and help repair damaged nerves? I’m referring here mostly to essential oils and natural painkillers.

Essential oils for neuropathy

A recent scientific study report a 66% drop in diabetes-related peripheral neuropathy pain on patients who got their feet massaged with essential oils, compared to a 9% drop only for others. Aromatherapy has been used for centuries in traditional medicines to effectively reduce nerve pain, soothe the nervous system, and repair damaged nerves

Essential oils blend very well in creams and lotions and are totally compatible with CBD. They’re 100% natural and have very mild side effects. When shopping for CBD topicals for neuropathy, it’s a good idea to look for creams, salves, or lotions that also contain essential oils known to relieve nerve pain and repair damaged nerves such as: 

If you’re willing to try the synergy of CBD and essential oils to fight neuropathy pain, you should try Zatural CBD Hot Cream (with 20 plant extracts and essential oils including Helichrysum, Basil, Peppermint, and Chamomille) or CBDMedic Pain-Relief CBD massage Oil (with Frankincense and Myrrh essential oils). Know more about essential oils for neuropathy:

Like CBD, essential oils and aromatherapy products are not FDA-regulated. They should be used with caution. Neuropathy is a serious condition. This article does not represent medical advice and should not be interpreted as such. Ask for your doctor’s advice before applying anything on your feet.

Cooling effects, Menthol, and cryotherapy for nerve pain

Cold is a natural analgesic that can considerably reduce the sensation of pain. Many people suffering from peripheral neuropathy find relief in cold compresses or natural ingredients with a cooling effect. That’s why most diabetic foot creams and most of the above CBD creams for nerve pain contain either menthol crystals or peppermint essential oil. Their cooling effect helps alleviate neuropathy symptoms such as burning sensation, tingling, or numbness. 

More pain-relieving ingredients to look for

For even stronger pain relief, know that CBD combines very well with more renowned natural or non-natural pain-killing ingredients such as Arnica, Camphor, Lidocaine, and others. Many CBD topicals for pain smartly use the synergy between these ingredients for optimal results. 

Aloe Vera & nourishing moisturizers

When living with diabetes and neuropathy, you must keep the skin of your feet nourished and hydrated. Dry skin tends to crack and gets wounds that can get infected and lead to serious foot problems. If besides relieving pain, your CBD foot cream nourishes your skin, it’s a valuable bonus! If you have dry skin, look for CBD creams and lotions that contain shea butter, or quality natural oils such as jojoba, coconut, argan, or others. 

There’s little way around Aloe Vera when it comes to pain relief topicals, and the CBD companies know it. Most CBD creams that I’ve selected for nerve pain contain aloe vera. It has strong anti-inflammatory, pain-relief, hydrating, and soothing properties, and it provides a slightly cooling effect that is very pleasant on neuropathic feet. 


I hope this article has helped you out. Please, do not hesitate to ask, share, and criticize in the comment section below! 

Share on facebook
Share on twitter
Share on email
Share on whatsapp
Share on print

Follow Sweet Trip!

Search a topic

#1 Diabetic Footwear Company

60-days wear test 

100% satisfaction guaranteed

Orthofeet diabetic shoes brand review

Visit Website

Best Foot Cream For Diabetic Neuropathy

About the author

Laura Pandolfi diabetes blogger

I’m Laura. Type 1 diabetic. Mother. Traveler. Writer. Researcher. I started this blog 5 years ago to investigate diabetes-related topics and share different views on the subject. I hope you find it useful!

Your subscription could not be saved. Please try again.
Your subscription has been successful.

Subscribers-only 😉

Like 23,500 other diabetics, you can register to our newsletter and receive great tips, how-to's, recipes... and suscribers-only coupons on our partner's products for diabetes.