The 10 Best Neuropathy Creams for to Relieve Nerve Pain 

Last updated on March 1, 2022 – Published on October 26, 2021
Neuropathy foot cream

You’re suffering from symptoms such as shooting pain, cramps, burning feet, prickling, tingling, extreme sensitivity to touch, or numbness in your feet? You might have peripheral neuropathy caused by diabetes, chemotherapy, or other diseases. 

Over-the-counter neuropathy creams and topical nerve pain relief solutions are accessible alternatives to oral medications and injections. Most pain-creams for neuropathy use strong pain relievers like capsaicin, lidocaine, CBD oil, menthol, arnica, and essential oils. 

Let’s dig in this selection of the 11 most effective creams for neuropathy to find the one that would work best for you!

Neuropathy is a serious condition. You should first seek advice and proper diagnosis from your medical team. You might need medical treatment. When living with diabetic neuropathy, take extra care of your feet and don’t forget your annual diabetic foot exam.

1. Best Overall Neuropathy Cream

PharmaPulse Neuropathy Nerve Therapy & Relief Cream

PharmaPulse Neuropathy & Soothing Nerve Formula

PharmaPulse Neuropathy Nerve Pain Relief is an arnica and aloe vera-based cream that has proven its efficiency for years now. It has been specially developed for neuropathy and nerve pain. 

It has a minimal yet very efficient composition, with only a few ingredients including soothing aloe vera, anti-inflammatory Arnica extract, and no artificial perfume. Besides being an efficient topical pain-reliever, this cream also helps boost blood circulation and provides a cooling effect that’s well-appreciated by neuropathic feet. In the long run, it nourishes and rejuvenates the skin.

It’s a highly concentrated formula. You only need to apply a tiny bit, and one jar goes a long way!

2. Highest Strength CBD Cream for Nerve Pain

Zatural CBD Hot Cream for Pain

Zatural CBD Hot Cream: Best Neuropathy Ingredients Combo!

Even though it does not say it, if you look at the list of ingredients, it looks like Zatural CBD Hot Cream has been specially and perfectly formulated for neuropathy

Cannabidiol (CBD) is steadily gaining popularity among people suffering from chronic pain, including nerve pain. Whether applied topically or ingested in the form of CBD gummies, the THC-free version of the Cannabis plant is a new alternative to numerous painkillers

If you’re willing to try CBD for diabetic neuropathy, Zatural CBD Hot Cream is your best bet. Not only is it infused with 2000 mg of premium-quality organic broad-spectrum CBD, but it also contains plenty of essential oils and plant extracts with numerous benefits for damaged nerves.

Zatucal CBD Hot cream for neuropathy

Helichrysum flower oil helps regenerate damaged nerves and connective tissues. Basil leaf oil is known to be a good nerve tonic, while Peppermint oil helps boost blood circulation. The Menthol crystals will provide a strong cooling effect that’s highly beneficial to ease nerve pain. You’ll also find Chamomile essential oil and Aloe vera extract for incredible soothing and calming properties

This cream is a very strong topical pain-reliever. If you want to try something a bit “lighter”, choose the CBD 250mg first. The only downside is the price, but quality CBD topicals are all expensive. 

3. Best Hemp Cream for Nerve Pain & Neuropathy

PureHemp Intensive Relief Rub with Menthol & Arnica

Pure Hemp Intensive Relief Rub with Menthol & Arnica

Pure Hemp Intensive Relief Rub is an amazing product formulated to relieve chronic pain caused by diabetic neuropathy, arthritis, and other chronic conditions. It’s based on premium-quality hemp oil infused with CBD Isolate, the purest form of CBD without any traces of THC. If you’re still skeptical about Cannabidiol, I invite you to read our in-depth article about CBD for diabetes and neuropathy

The additional cooling menthol & arnica extracts make it a rapid and powerful pain reliever, while the Frankincense essential oil specifically targets nerve pain. It contains 10% of Emu oil, which is a potent topical anti-inflammatory and helps heal wounds, prevent foot ulcers, and stimulate skin cells regeneration. There’s also a great quantity of aloe vera extract to soothe skin discomforts and itchiness, for an overall very good moisturizer for diabetic skins.

Pure Hemp Pain Relief Rub is guaranteed without any traces of THC. The company currently offers a 50% discount on all their products!

More Neuropathy Topical Relievers from Pure Hemp:

4. Best Nerve Pain & Burning Feet Treatment Cream

MagniLife Foot Cream for Burning, Tingling, Itching, and Shooting Pain

MagniLife Foot Cream for Burning, Tingling, Itching, & Shooting Pain

MagniLife Foot Cream has been a best-seller for years among people suffering from burning sensation, itching, tingling, stabbing or shooting pain in the feet. The cream has been specially formulated to relieve these common neuropathy symptoms. It’s a good topical analgesic, as well as a great moisturizer for your skin. It deeply repairs severely dry skin and cracked skin, and helps remove calluses. The small compact format allows you to carry it everywhere and to conveniently apply when needed.

5. Best Essential Oil Blend for Peripheral Neuropathy

Vibrant Blue Oils’ Nerve Repair Blend for Damaged Nerves

Vibrant Blue Oils' Nerve Repair Blend for Damaged Nerves

This essential oil blend has proven to repair damaged nerved, relieve nerve pain, ease inflammation, stimulate blood flow, reduce swelling, and help regenerate new cells. The perfect aromatherapy combo for neuropathy pain and pinched nerves!

Use 2-3 drops of the Nerve Repair blend to gently massage the affected area (usually the feet or hands in case of peripheral neuropathy). You can also apply it on a cold compress and let it rest for about 15 minutes. Apply 2-3 times a day.

6. Best Neuropathy Rubbing Oil

Frankincense & Myrrh Rubbing Oil for Neuropathy Pain Relief

Frankincense & Myrrh Rubbing Oil for Nerve Pain

If you prefer rubbing your feet in oil rather than applying foot cream, this rubbing oil has been specially formulated to relieve neuropathic pain caused by diabetes, chemotherapy, and other peripheral nerve conditions. 

It’s an all-natural foot care product made with homeopathic ingredients and essential oils selected for their high efficiency to relieve neuropathy symptoms such as shooting pain, burning, prickling, and numbness in feet and hands. 

Frankincense essential oil (Boswellia Carterii) has strong sedative and anti-inflammatory compounds. It’s also believed to improve message transmission from the nerves to the brain which ultimately reduces nerve pain. Myrrh essential oil (Commiphora Myrrha) is a strong pain relief and anti-swelling ingredient. It interacts with our opioids receptors to decrease the brain’s perception of pain, and considerably reduces swelling. 

Costumers report strong and long-lasting effects on diabetic nerve pain! You can use it up to 4 times a day by gently massaging your feet.

Frankincense & Myrrh Neuropathy Lotion

If you like the formula but prefer using moisturizing lotion than rubbing oil, check out Frankincense & Myrrh Intensive Therapy Foot Lotion:

7. Best Capsaicin Cream for Neuropathy

Nervex Arnica & Capsaicin Cream for Nerve Pain

Nervex Arnica & Capsaicin Cream for Nerve Pain

Capsaicin is an active ingredient found in chili peppers. It’s a strong pain reliever that works by first stimulating the intensity of pain signals to provoke the release of our natural body pain-relievers. It has proven to work great on nerve pain. High-dose capsaicin topical pain treatments are available on medical prescription, but you can get low-dose over-the-counter capsaicin neuropathy creams such as the one from Nervex. 

Nervex nerve pain relief lotion is based on Capsaicin and Arnica active ingredients, as well as high doses of Vitamin B12, Vitamin E, and Andrographis extract to lessen neuropathy symptoms such as painful numbness, burning feet, tingling, and muscle spams. It also supports synapse repair and healthy nerve cells

Besides, it’s a good skin moisturizer that deeply rehydrates diabetics’ dry skin. You get 30 safe measured applications of lotion in a convenient airless dispenser. 

8. Best Cooling Menthol Ointment for Nerve Pain

Nuturna Arnica & Menthol Intensive Topical Concentrate for Nerve Pain

Nuturna Arnica & Menthol Intensive Topical Ointment for Nerve Pain

Nuturna Menthol ointment for neuropathy is a great all-in-one over-the-counter topical treatment for damaged and painful nerves. Its formula is made not only to relieve neuropathy symptoms, but also to address the causes of these symptoms. The ingredient combinations help boost blood circulation, stimulate the nerves, and increase sensitivity

The menthol crystals provide an intense cooling therapy. Cold is a natural analgesic and anti-inflammatory that considerably reduces the brain’s perception of pain and helps reduce swelling.

You’ll also benefit from Arnica extract, one of the most popular homeopathic pain reliever, as well as Vitamins, MSM (Methylsulfonylmethane), and soothing aloe vera. 

9. Fast-acting Nerve Renew Cream

Nerve Renew Cream with Capsaicin & Camphor

Nerve Renew cream is a fast-acting topical pain reliever that soothes nerve discomfort and supports normal nerve function. It decreases most common neuropathy symptoms intensity such as numbness, burning feet, and tingling sensation. 

The Capsaicin it contains warms the feet and legs to relieve pain, while Camphor stimulates nerve endings, relieves pain and itching, and fight fungus infection in between the toes. It’s a rich formula and a great skin moisturizer too. 

Nerve Renew Nerve Advanced Nerve Support Capsules

Nerve Renew cream is frequently bought together with Nerve Renew Advanced Support supplement capsules with R-Alpha Lipoic Acid. 

10. Livrelief Ultra-Strength Nerve Pain Cream

Dr. Joe's LivRelief Cream for Neuralgia & Diabetic Neuropathy

Dr. Joe’s LivRelief Nerve Pain Relief Cream is the only one I know of that contains Rutin, a bioflavonoid found in fruits and vegetables, powerful antioxidant and anti-inflammatory that blocks 5 pain pathways. It also contains Capsaicin which is proven to efficiently relieve neuropathy pain by warming the feet and legs. 

Formulated to distress neuropathy symptoms, numbness, and hypersensitivity, it’s a great topical that customer reviews highly recommend. 

11. Diabasens Leg & Foot Relief Cream for Diabetic Neuropathy

DiabaSens Nerve Relief Diabetic Foot Cream with Capsaicin

DiabaSens is a patented advanced over-the counter pain-relieving cream specially formulated for diabetic neuropathy. Laboratory tests show that it may increase sensitivity and improve blood flow. 

It provides a warming sensation on the feet and legs which most neuropathy patients find soothing. It’s also a good skin moisturizer that helps repair severely dry and cracked skin.